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Sunday sees the initial Wear-Tyne derby since 2024, but which side will celebrate – the Black Cats or the Magpies?
"During the bulk of last season, no one would have predicted the Wearside club getting promoted and challenging with Eddie Howe's Newcastle, never mind being above them in the table," remarked analyst Chris Sutton.
"It is very different now, and the way they play leads me to believe they've got a solid shot."
He is offering scoreline guesses for all 380 Premier League games this season, in competition with AI, readers and a assortment of guests.
For this weekend's fixtures, he takes on England Gaming star Daniel 'Stingray' Ray.
Ray is going for glory for the national gaming squad – the Football Association's formal esports team – at the EA Sports FC Uefa eEuro 2025 finals tournament, which will occur at Twickenham Stadium on Saturday.
You can watch Uefa's video platform, Instagram Live and short-form video channels, as well as the official Twitch channel and YouTube and England's Twitch.
Are you in alignment with their predictions? Feel free to submit your own projections below.
The most commonly selected scoreline selected for each game is used in the tables at the bottom of this page.
Predicting the right outcome (selecting a win, draw or defeat) is worth 10 points. An accurate scoreline earns forty points.
Ray, who competes for his club side and the Premier League champions as well as England, is entering the fray at the eEuros finals after passing the qualifying.
The final eight competitors will fly the flag at the finals in a knockout format, competing for a six-figure prize fund and a prestigious spot in the global championship qualifiers, with Denmark's Anders Vejrgang looking to retain the title he won last year.
"My mindset is really good for it," Ray stated. "I have a really good coach by my side and preparation has been going well.
"It's always an honour to play for your country. Naturally when you are younger, you imagine doing it as an professional footballer, but when you pursue a career in this field and there is an chance to represent England, donning the national jersey is something unique.
"I beat Vejrgang 9-4 in qualifying to get here. I've played against him over the course of the season just in practice, and in other tournaments before - but I'd never beaten him in a tournament before.
"I believe he is the top competitor in the world so defeating him in a tournament like this just delivers a huge surge of confidence."
Premier League Weekend Preview
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
Chelsea were excellent against the Gunners at the end of November, when they got a draw after going down to 10 men, and it seemed they've turned a corner, they could potentially be title contenders.
However, since that game, however, they were beaten physically by Leeds, looked lethargic against Bournemouth and this week got turned over by Atalanta in the Champions League.
So manager Enzo Maresca is in need of a win here to restore momentum, but it is a tough ask because the Toffees are such a potent team.
Kiernan Dewsbury-Hall and Iliman Ndiaye are playing exceptionally and Everton have got a bit of momentum at the moment.
Based on recent performances you would probably back the visitors, while the most sensible prediction would likely be a draw, but I'm going against logic.
Chelsea haven't given me any good cause to back them recently, but I just have a feeling Chelsea will emerge victorious because they are at home and they are due a win.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'll be at this game and it will be intriguing to see what we get from the Reds.
I was delighted for Reds boss Arne Slot to get such a crucial result at Inter Milan on Tuesday following all the discussion with Mohamed Salah this week.
Slot should not have to put up with that nonsense. I know Salah has been a icon for Liverpool but essentially Slot just wants to win games and there is no ulterior motive in his team selection.
Liverpool changed their formation against Inter and went with a midfield diamond formation and two up top.
All the talk is going to be talking about whether Salah is back for this game, but the only way he is going to be brought back into the fold is if he says sorry.
Slot's primary concern will be on winning this game, but it is a tough one.
You could argue it is the same for most teams but I find Brighton so hard to predict. I always feel they have got a goal in them, but they are defensively susceptible too.
The Merseysiders need to get back to stringing wins together, but I am not sure how much their energy spent at the San Siro will have affected their stamina.
I've selected a couple of Brighton players in my Fantasy Premier League side, so they will almost certainly blank - but I do fancy them to get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Wearside club have had the opportunity to rest while Newcastle had to battle intensely against Bayer Leverkusen on Wednesday, only to concede a late equaliser late on.
Aside from their brilliant performance against Everton a couple of weeks ago, Newcastle's away form has been inconsistent, particularly straight after they've played in the Champions League.
The pattern suggests that pattern to continue on Sunday, and their fatigue is likely to be a significant issue in how this game goes because of Sunderland's intensity.
Their match against Arsenal demonstrated how relentless Regis le Bris's side are. They overpowered the Gunners, and it was a joy to watch.
Commentators talks about how Granit Xhaka has been phenomenal for the Black Cats, and he has been excellent, but Noah Sadiki, who plays alongside him, has also been one of the signings of the season and warrants praise too.
All signs point to this being the best game|most exciting fixture